Milwaukee Bucks head coach Mike Budenholzer told reporters following his team's 105-99 defeat at Fiserv Forum that the All-Star forward injured his right ankle late in the fourth quarter.
The Greek Freak was replaced by George Hill with 1:12 remaining in the fourth quarter but returned with 34.7 seconds left and the Bucks trailing 100-97.
He finished with a team-high 24 points on 9-of-18 shooting along with six rebounds, six assists, and a rejection in in 39 minutes of action.
"I think we had a chance to win it, win the game today, but we didn't," said Antetokounmpo. "Obviously, you know, I'm pissed. I'm not going to lie to you. You just gotta keep your head up, keep believing in yourself, keep having that confidence."
The Bucks will try to stave off elimination on Saturday as the series heads back to Toronto for Game 6.