The Chiefs listed Watkins as questionable due to a foot injury after he returned to practice on Tuesday. The wideout hasn't played since the team's Week 11 shootout loss to the Los Angeles Rams.
Berry is dealing with a heel injury. He returned to the lineup in Week 15 after being sidelined since Week 1 of the 2017 campaign with a ruptured Achilles, playing two games before sitting out the regular-season finale. Ware missed the final three games of the regular season with a hamstring injury.
Watkins' return provides a boost to Kansas City's dynamic passing attack, led by Patrick Mahomes, that already features Tyreek Hill, Travis Kelce, and Chris Conley. The Colts finished with the NFL's 10th-ranked scoring defense during the regular season.
The 25-year-old recorded 40 receptions for 519 yards and three touchdowns over 10 games in 2018 after signing a three-year, $48-million contract as a free agent in the offseason.