Miller received a standing ovation from the crowd in Minnesota to begin the game.
The Wild lined up postgame to shake Miller's hand before he stepped off the ice for the last time.
Miller also shared an emotional moment with his parents.
He finishes his career as the winningest American goalie in NHL history with 391 victories. Miller won the Vezina Trophy in 2010 while playing with the Buffalo Sabres, and he backstopped Team USA to a silver medal at the 2010 Olympics.
His 18-year career ends with a 391-289-96 record, a 2.64 goals-against average, and a .914 save percentage.